Friday, August 25, 2017

CRISPR/Cas9




"And that which thou sowest, thou sowest not that body that shall be, but bare grain, it may chance of wheat, or of some other grain: But God giveth it a body as it hath pleased him, and to every seed his own body. All flesh is not the same flesh: but there is one kind of flesh of men, another flesh of beasts, another of fishes, and another of birds" (1Co 15:37-39).

But "man" has determined to give whatsoever flesh a body as it hath pleased him!

"Professing themselves to be wise, they became fools, [using transgenesis CRISPR/Cas9 genome editing to create "transgenic" variants of themselves, changing] the glory of the uncorruptible God into an image made like to corruptible man, and to birds, and fourfooted beasts, and creeping things. Wherefore God also gave them up... ." (cf. Romans 1:22-24).


Last September [2016], ... the National Institutes of Health (NIH) announced it would not support studies involving such “human-animal chimeras”... . The agency, in a statement, said it was worried about the chance that animals’ “cognitive state” could be altered if they ended up with human brain cells.
The NIH action was triggered after it learned that scientists had begun such experiments with support from other funding sources, including from California’s state stem-cell agency. The human-animal mixtures are being created by injecting human stem cells into days-old animal embryos, then gestating these in female livestock.
Based on interviews with three teams, two in California and one in Minnesota, MIT Technology Review estimates that about 20 pregnancies of pig-human or sheep-human chimeras have been established during the last 12 months in the U.S., though so far no scientific paper describing the work has been published... .1
When the NIH relented, and allowed researchers to receive federal funds to make "part human, part animal embryos," researchers still criticized the agency for creating “a threat to progress” and casting "a shadow of negativity” because of proposed changes to existing stem cell guidelines, e.g., scrutiny of "experiments designed to create animals with human brain cells or human brain tissue," or a “substantial contribution” or “substantial functional modification” to the brain of an animal.
The worry is that the animals might turn out to be a little too human for comfort, say ending up with human reproductive cells, patches of people hair, or just higher intelligence. “We are not near the island of Dr. Moreau, but science moves fast,” NIH ethicist David Resnik said during the agency’s November meeting. “The specter of an intelligent mouse stuck in a laboratory somewhere screaming ‘I want to get out’ would be very troubling to people.”1

As avant-garde interventionists practice their imprecise art of creation — beasts part man and part not — human-animal chimeras are gestating in America; the guardé maintaining a self-imposed moratorium of silence. Few technical abstracts and associated research papers have been published in recent months — those that have, were not reported in the media since the January MIT Technology Review article. Obviously, those affiliated with this spiritually reprehensible endeavor prefer to work without peer or other review, as they profane the "Imago Dei."
"And God said, Let us make man in our image, after our likeness: and let them have dominion over the fish of the sea, and over the fowl of the air, and over the cattle, and over all the earth, and over every creeping thing that creepeth upon the earth. So God created man in his own image, in the image of God created he him; male and female created he them" (Genesis 1:26-27).

 1Regalado, Antonio. 2016. Senior Editor, Biomedicine: Human-Animal Chimeras Are Gestating on U.S. Research Farms." MIT Technology Review." January 6. https://www.technologyreview.com/s/545106/human-animal-chimeras-are-gestating-on-us-research-farms/.

2By Hiroshi Nishimasu, F. Ann Ran, Patrick D. Hsu, Silvana Konermann, Soraya I. Shehata, Naoshi Dohmae, Ryuichiro Ishitani, Feng Zhang, and Osamu Nureki [CC BY-SA 3.0 (http://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons https://commons.wikimedia.org/wiki/File%3ACrystal_Structure_of_Cas9_in_Complex_with_Guide_RNA_and_Target_DNA.jpg https://upload.wikimedia.org/wikipedia/commons/7/7f/Crystal_Structure_of_Cas9_in_Complex_with_Guide_RNA_and_Target_DNA.jpg

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